Quality of and methodological heterogeneity in COVID-19 vaccine safety studies - Case study of Bell's palsy safety signal

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Master Thesis

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Abstract

In this systematic review, the methodological quality of published observational studies evaluating risk of Bell’s palsy following COVID-19 vaccination was assessed, the heterogeneity across studies addressing similar questions was characterized, and finally, the sources of heterogeneity, focussing on the impact of study design specification, was investigated.

Keywords

Bell's palsy; COVID-19; methodological quality; heterogeneity

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